Sirard Marc-André

361: Ispada J, de Lima CB, da Fonseca-Junior AM, Dos Santos EC, Martin H, Ross PJ, SIRARD MA, Milazzotto MP. Alpha-ketoglutarate modulates the reprogramming of mitochondrial and nuclear DNA methylation during the earliest stages of the bovine preimplantation embryo development†. Biol Reprod. 2025 Sep 15;113(3):527-540. doi: 10.1093/biolre/ioaf119. PMID: 40817811.

360: SIRARD MA. The effects of breeding young bulls and cows in vitro. Anim Reprod. 2025 Aug 11;22(3):e20250047. doi: 10.1590/1984-3143-AR2025-0047. PMID: 40791782; PMCID: PMC12338970.

359 : Marques JCS, Maciel JPO, Conceicao RS, Moore S, Tremblay P, SIRARD MA, Cerri RLA. Embryo response to different progesterone concentrations during superovulation of Holstein heifers: a transcriptomic analysis. Theriogenology. 2025 Nov;247:117564. doi: 10.1016/j.theriogenology.2025.117564. Epub 2025 Jul 1. PMID: 40633436.

358 : Zhang Y, SIRARD MA. From sperm to offspring: epigenetic markers for dairy herd fertility. Biol Reprod. 2025 Mar 29:ioaf056. doi: 10.1093/biolre/ioaf056.. PMID: 40156927.

357: Bouzeraa L, Martin H, Dufour P, Marques JCS, Cerri R, SIRARD MA. Epigenetic insights into fertility: involvement of immune cell methylation in dairy cows reproduction. Biol Reprod. 2025 Feb 5:ioaf020. doi: 10.1093/biolre/ioaf020. Epub ahead of print. PMID: 39908274.

356: Ruggeri E, Klohonatz K, Durrant B, SIRARD MA. Identification and Preliminary Analysis of Granulosa Cell Biomarkers to Predict Oocyte In Vitro Maturation Outcome in the Southern White Rhinoceros (<i>Ceratotherium simum simum</i>). Animals (Basel). 2024 Dec 7;14(23):3538. doi: 10.3390/ani14233538. PMID: 39682503; PMCID: PMC11640850.

355: Vargas LN, Zhang Y, Wu C, Martin H, Alonso Goulart V, Plessis C, SIRARD MA. Unraveling the role of sperm retained histones in bull fertility and daughter fertility. Theriogenology. 2024 Dec;230:299-304. doi: 10.1016/j.theriogenology.2024.09.023. Epub 2024 Sep 25. PMID: 39366208.

354: Bouzeraa L, Martin H, Plessis C, Dufour P, Marques JCS, Moore S, Cerri R, SIRARD MA. Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows.Epigenetics. 2024 Dec;19(1):2391602. doi: 10.1080/15592294.2024.2391602. Epub2024 Aug 16. PMID: 39151128.

353: Klohonatz K, Durrant B, SIRARD MA, Ruggeri E. Granulosa cells provide transcriptomic information on ovarian follicle dynamics in southern white rhinoceros. Sci Rep. 2024 Aug 20;14(1):19321. doi: 10.1038/s41598-024-70235-7.PMID: 39164442; PMCID: PMC11336098.

352: 1Haimon MLJ, Estrada-Cortés E, Amaral TF, Martin H, Jeensuk S, Block J, Heredia D, Venturini M, Santos Rojas C, Gonella-Diaza A, DiLorenzo N, Scheffler T, Dufour P, SIRARD MA de Melo GD, Pohler KG, Hansen PJ. Provision of choline chloride to the bovine preimplantation embryo alters postnatal body size and DNA methylation. Biol Reprod. 2024 Jun 10:ioae092. doi: 10.1093/biolre/ioae092. Epub ahead of print. PMID: 38857381.

351: Wang M, Bissonnette N, Laterrière M, Dudemaine PL, Gagné D, Roy JP SIRARD MA, Ibeagha-Awemu EM. DNA methylation haplotype block signatures responding to Staphylococcus aureus subclinical mastitis and association with production and health traits. BMC Biol. 2024 Mar 14;22(1):65. doi: 10.1186/s12915-024-01843-y.PMID: 38486242; PMCID: PMC10941392.

350: Zhang Y, Labrecque R, Tremblay P, Plessis C, Dufour P, Martin H, SIRARD MA. Sperm-borne tsRNAs and miRNAs analysis in relation to dairy cattle fertility. Theriogenology. 2024 Feb;215:241-248..theriogenology..11.029. Epub 2023 Dec 9. PMID: 38100996.

349: Teplitz GM, Lorenzo MS, Cruzans PR, Olea GB, Salamone DF, Bastien A, Robert C, SIRARD MA, Lombardo DM. Coculture with porcine luteal cells during invitro porcine oocyte maturation affects lipid content, cortical reaction andzona pellucida ultrastructure. Reprod Fertil Dev. 2024 Jan;36(3):10.1071/RD23150. PMID: 38096792.

348: Tutt DAR, Guven-Ates G, Kwong WY, Simmons R, Sang F, Silvestri G, Canedo- Ribeiro C, Handyside AH, Labrecque R, SIRARD MA, Emes RD, Griffin DK, Sinclair KD. Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes. Front Endocrinol (Lausanne). 2023 Oct 23;14:1280847. doi:10.3389/fendo.2023.1280847. PMID: 38027209; PMCID: PMC10647927.

347: Zhang Y, Plessis C, Prunier J, Martin H, Labrecque R, SIRARD MA. DNA methylation profiles in bovine sperm are associated with daughter fertility. Epigenetics. 2023 Dec;18(1):2280889. doi: 10.1080/15592294.2023.2280889. Epub 2023 Nov 20. PMID: 38016027; PMCID: PMC10732624.

346: van Staaveren N, Oliveira HR, Houlahan K, Chud TCS, Oliveira GA Jr, Hailemariam D, Kistemaker G, Miglior F, Plastow G, Schenkel FS, Cerri R, SIRARD MA, Stothard P, Pryce J, Butty A, Stratz P, Abdalla EAE, Segelke D, Stamer E  Thaller G, Lassen J, Manzanilla-Pech CIV, Stephansen RB, Charfeddine N, Garcia- Rodriguez A, González-Recio O, López-Paredes J, Baldwin R, Burchard J, Gaddis K, Koltes JE, Peñagaricano F, Santos JEP, Tempelman RJ, VandeHaar M, Weigel K, White H, Baes CF. The Resilient Dairy Genome Project – a general overview of methods and objectives related to feed efficiency and methane emissions. J Dairy Sci. 2023 Sep 8:S0022-0302(23)00617-3. doi: 10.3168/jds.2022-22951. Epub PMID: 37690718.

345: Marques JCS, Maciel JPO, Denis-Robichaud J, Conceicao RS, Bega AM, Moore S, SIRARD MA, Baes CF, Cerri RLA. The effect of progesterone concentrations during superovulation of Holstein heifers in a randomized trial. J Dairy Sci. 2023 Aug 23:S0022-0302(23)00461-7. doi: 10.3168/jds.2022-23065. Epub ahead of print. PMID: 37641352.

344: de Lima CB, Martin H, Pecora Milazzotto M, SIRARD MA. Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development. Epigenetics. 2023  Dec;18(1):2241010. doi: 10.1080/15592294.2023.2241010. PMID: 37523633; PMCID: PMC10392754.

343: Wang M, Bissonnette N, Laterrière M, Gagné D, Dudemaine PL, Roy JP, SIRARD MA, Ibeagha-Awemu EM. Genome-Wide DNA Methylation and Transcriptome Integration Associates DNA Methylation Changes with Bovine Subclinical Mastitis Caused by<i>Staphylococcus chromogenes</i>. Int J Mol Sci. 2023  Jun 20;24(12):10369. doi:10.3390/ijms241210369. PMID: 37373515; PMCID: PMC10299661.

342: Wang M, Bissonnette N, Laterrière M, Dudemaine PL, Gagné D, Roy JP, SIRARD MA, Ibeagha-Awemu EM. Gene co-expression in response to Staphylococcus aureus infection reveals networks of genes with specific functions during bovinesubclinical mastitis. J Dairy Sci. 2023 Aug;106(8):5517-5536. doi:10.3168/jds.2022-22757. Epub 2023 Jun 7. PMID: 37291036.

341: Arjoune A, Alsaleh AB, Messaoudi SA, Chelbi H, Jelassi R, Assidi M, Najar T, Haddad B, SIRARD MA . Analysis of “MTNR1A” Genetic Polymorphisms and Their Association with the Reproductive Performance Parameters in Two Mediterranean Sheep Breeds. Animals (Basel). 2023  Jan 28;13(3):448. doi: 10.3390/ani13030448. PMID: 36766337; PMCID: PMC9913639.

340 : Bruna de Lima C, Cristina Dos Santos É, SIRARD MA. DOHaD: A Menagerie of Adaptations and Perspectives: The interplay between early embryo metabolism and mitoepigenetic programming of development. Reproduction. 2023  May 25;166(1):F15-F26. doi: 10.1530/REP-22-0424. PMID: 37140978.

339: Lafontaine S, Labrecque R, Blondin P, Cue RI, SIRARD MA. Comparison of cattle derived from in vitro fertilization, multiple ovulation embryo transfer, and artificial insemination for milk production and fertility traits. J Dairy Sci. 2023  Apr 5:S0022-0302(23)00161-3. doi: 10.3168/jds.2022-22736. Epub ahead of print. PMID: 37028966.

338 : Zhang Y, Bruna de Lima C, Labrecque R, SIRARD MA. Whole genome DNA methylation analysis of the sperm in relation to bull fertility. Reproduction. 2023  Mar 1:REP-22-0283. doi: 10.1530/REP-22-0283. Epub ahead of print. PMID:36912765.

337 : Lafontaine S, Cue RI, SIRARD MA. Gestational and health outcomes of dairy cows conceived by assisted reproductive technologies compared to artificial insemination. Theriogenology. 2023  Mar 1;198:282-291. doi: 10.1016/j.theriogenology.2023.01.002. Epub 2023 PMID: 36634442.

336: Wang M, Bissonnette N, Laterrière M, Dudemaine PL, Gagné D, Roy JP, Zhao X, SIRARD MA, Ibeagha-Awemu EM. Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis. J Anim Sci Biotechnol. 2022 Nov 7;13(1):136. doi: 10.1186/s40104-022-00779-z. PMID: 36336691; PMCID: PMC9639328.

335: Arjoune A, SIRARD MA. The genomic response of human granulosa cells (KGN) to melatonin and specific agonists/antagonists to the melatonin receptors. Sci Rep. 2022 Oct 20;12(1):17539. doi: 10.1038/s41598-022-21162-y. PMID: 36266374; PMCID: PMC9584952.

334: SIRARD MA. Why is the human ovary aging faster than other organs? Women Health. 2022 Aug;62(7):577-579. doi: 10.1080/03630242.2022.2105776. PMID: 35938358.

333: Ruggeri E, Young C, Ravida N, SIRARD MA, Krisher R, de la Rey M, Herbst C, Durrant B. Glucose consumption and gene expression in granulosa cells collected before and after in vitro oocyte maturation in the southern white rhinoceros (Ceratotherium simum simum). Reprod Fertil Dev. 2022 Aug;34(13):875-888. doi: 10.1071/RD22071. PMID: 35871524.

332: Lafontaine S, SIRARD MA. IGF2R, KCNQ1, PLAGL1, and SNRPN DNA methylation is. completed in bovine by the early antral follicle stage. Mol Reprod Dev. 2022 Jun13. doi: 10.1002/mrd.23621. Epub ahead of print. PMID: 35698757.

331: Shi M, SIRARD MA. Metabolism of fatty acids in follicular cells, oocytes, and blastocysts. Reprod Fertil. 2022 Apr 29;3(2):R96-R108. doi: 10.1530/RAF-21-0123.PMID: 35706579; PMCID: PMC9175597.

330: SIRARD MA. How the environment affects early embryonic development. Reprod Fertil Dev. 2021 Dec;34(2):203-213. doi: 10.1071/RD21266. PMID: 35231267.

329: Voisine J, SIRARD MA. Ethics and animal reproductive technologies. Reprod Fertil Dev. 2021 Dec;34(2):214-233. doi: 10.1071/RD21284. PMID: 35231384.

328: Hallberg I, Persson S, Olovsson M, Moberg M, Ranefall P, Laskowski D,Damdimopoulou P, SIRARD MARüegg J, Sjunnesson Y. Bovine oocyte exposure to perfluorohexane sulfonate (PFHxS) induces phenotypic, transcriptomic, and DNA methylation changes in resulting embryos in vitro. Reprod Toxicol. 2022 Feb 24:S0890-6238(22)00023-doi:10.1016/j.reprotox.2022.02.004.  Epub ahead ofprint. PMID: 35219833.

327: SIRARD MA. The two-step process of varian follicular growth and maturation in mammals can be compared to a fruit ripening where quality depends on the second step. Biol Reprod. 2021 Dec 23:ioab236. doi: 10.1093/biolre/ioab236. Epub ahead of print. PMID: 34939644.

326: Zhang Y, SIRARD MA. Epigenetic inheritance of acquired traits through DNA methylation. Anim Front. 2021 Dec 17;11(6):19-27. doi: 10.1093/af/vfab052. PMID:34934526;

325: Tremblay PG, Fortin C, SIRARD MA. Gene cascade analysis in human granulosa tumor cells (KGN) following exposure to high levels of free fatty acids and insulin. J Ovarian Res. 2021 Dec 20;14(1):178. doi: 10.1186/s13048-021-00934-6.PMID: 34930403.

324: Shi M, SIRARD MA. Effects of NEFAs during IVM on pig embryos from granulosa cell-cocultured oocytes. Mol Reprod Dev. 2021 Nov 28. doi: 10.1002/mrd.23548.Epub ahead of print. PMID: 34841613.

323: Hallberg I, Persson S, Olovsson M, SIRARD MA, Damdimopoulou P, Rüegg J, Sjunnesson YCB. Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model. Toxicology. 2021 Nov 8:153028. doi: 10.1016/j.tox.2021.153028. Epub ahead of print. PMID: 34762985.

322: Shi M, SIRARD MA. Cocultured porcine granulosa cells respond to excess non-esterified fatty acids during in vitro maturation. J Ovarian Res. 2021 Oct 28;14(1):142. doi: 10.1186/s13048-021-00904-y. PMID: 34711256; PMCID:PMC8554973.

321: Rabaglino MB, Bojsen-Møller Secher J, SIRARD MA, Hyttel P, Kadarmideen HN.

Epigenomic and transcriptomic analyses reveal early activation of the HPG axis in in vitro-produced male dairy calves. FASEB J. 2021 Oct;35(10):e21882. doi:10.1096/fj.202101067R. PMID: 34460963.

320: Zhang Y, Chaput C, Fournier E, Prunier J, SIRARD MA. Comparing the whole genome methylation landscape of dairy calf blood cells revealed intergenerational inheritance of the maternal metabolism. Epigenetics. 2021 Jul 24:1-10. doi:10.1080/15592294.2021.1955188.

PMID:34304691.

319: Salilew-Wondim D, Tesfaye D, Rings F, Held-Hoelker E, Miskel D, SIRARD MA, Tholen E, Schellander K, Hoelker M. The global gene expression outline of the bovine blastocyst: reflector of environmental conditions and predictor of developmental capacity. BMC Genomics. 2021 Jun 3;22(1):408. doi: 10.1186/s12864-021-07693-0. PMID: 34082721; PMCID: PMC8176733.

318: Teplitz GM, Shi M, SIRARD MA, Lombardo DM. Coculture of porcine luteal cells during in vitro porcine oocyte maturation affects blastocyst gene expression and developmental potential. Theriogenology. 2021 Feb 25;166:124-134. doi: 10.1016/j.theriogenology.2021.02.014. Epub ahead of print. PMID: 33735666.

317: Shi M, SIRARD MA. Transcriptome and epigenome analysis of porcine embryos from non-esterified fatty acid-exposed oocytes. Domest Anim Endocrinol. 2021 Jan 16;76:106605. doi: 10.1016/j.domaniend.2021.106605. Epub ahead of print. PMID: 33631700.

316: Wu C, Blondin P, Vigneault C, Labrecque R, SIRARD MA. Sperm miRNAs- potential mediators of bull age and early embryo development. BMC Genomics. 2020 Nov 16;21(1):798. doi: 10.1186/s12864-020-07206-5. PMID: 33198638.

315: Wu C, SIRARD MA. Parental Effects on Epigenetic Programming in Gametes and Embryos of Dairy Cows. Front Genet. 2020 Oct 14;11:557846. doi:10.3389/fgene.2020.557846. PMID: 33173533; PMCID: PMC7591718.

314: Lafontaine S, Labrecque R, Palomino JM, Blondin P, SIRARD MA. Specific imprinted genes demethylation in association with oocyte donor’s age and culture conditions in bovine embryos assessed at day 7 and 12 post insemination. Theriogenology. 2020 Sep 24;158:321-330. doi:10.1016/j.theriogenology.2020.09.027. Epub ahead of print. PMID: 33010654.

313:  Manuel Palomino J, Grand FX, Vigneault C, Blondin P, SIRARD MA. Effects of follicular ablation and GnRH on synchronization of ovulation and conception rates in embryo recipient heifers. Anim Reprod Sci. 2020 Sep 14;221:106596. doi: 10.1016/j.anireprosci.2020.106596. Epub ahead of print. PMID: 32942212.

312 : de Lima CB, SIRARD MA. Mitoepigenetics: methylation of mitochondrial DNA is strand-biased in bovine oocytes and embryos. Reprod Domest Anim. 2020 Aug 1.doi: 10.1111/rda.13786. Epub ahead of print. PMID: 32738169.

311: Morin-Doré L, Blondin P, Vigneault C, Grand FX, Labrecque R, SIRARD MA. DNA methylation status of bovine blastocysts obtained from peripubertal oocyte donors. Mol Reprod Dev. 2020 Jul 17. doi: 10.1002/mrd.23399. Epub ahead of print. PMID: 32677283.

310: Fortin C, Hamilton S, Laforest M, Léveillé MC, SIRARD MA. Patients who failed to conceive following an IVF cycle can be clustered into different failure causes using gene expression hierarchical analysis. Biol Reprod. 2020 Jun doi: 10.1093/biolre/ioaa089. Epub ahead of print. PMID: 32483601.

309: Tremblay PG, SIRARD MA. Gene analysis of major signalling pathways regulated by gonadotropins in human ovarian granulosa tumour cells (KGN)† [published online ahead of print, 2020 May 19]. Biol Reprod. 2020 ;ioaa079. doi:10.1093/biolre/ioaa079

308: Lodde V, Garcia Barros R, Dall’Acqua PC, Dieci C, Robert C, Bastien A, SIRARD MA, Franciosi F, Luciano AM. Zinc supports transcription and improves meiotic competence of growing bovine oocytes. Reproduction. 2020May;159(6):679-691.PubMed PMID: 32191913.

307: Frasco, C.; Radmacher, M.; Lacroix, R.; Cue, R.; Valtchev, P.; Robert, C.; Boukadoum, M.; SIRARD MA. and Diallo, A. Towards an Effective Decision-making System based on Cow Profitability using Deep Learning.In Proceedings of the 12th International Conference on Agents and Artificial Intelligence – Volume 2: ICAART, ISBN 978-989-758-395-7, pages 949-958. (2020). DOI: 10.5220/0009174809490958

306: Bunel A, Nivet AL, Blondin P, Vigneault C, Richard FJ, SIRARD MA. The effects of LH inhibition with cetrorelix on cumulus cell gene expression during the luteal phase under ovarian coasting stimulation in cattle. Domest Anim Endocrinol. 2019 Dec 26;72:106429. doi: 10.1016/j.domaniend.2019.106429. [Epub ahead of print] PubMed PMID: 32320933.

305: SIRARD MA. Folliculogenesis and acquisition of oocyte competence in cows. Anim Reprod. 2019 Oct 23;16(3):449-454. doi: 10.21451/1984-3143-AR2019-0038. PMID: 32435288; PMCID: PMC7234107.

304: Chaput C, SIRARD MA. Embryonic response to high beta-hydroxybutyrate (BHB) levels in postpartum dairy cows. Domest Anim Endocrinol. 2019 Dec 31;72:106431. doi: 10.1016/j.domaniend.2019.106431. [Epub ahead of print] PubMed PMID: 32325411.

303: Wu C, Blondin P, Vigneault C, Labrecque R, SIRARD MA. The age of the bull influences the transcriptome and epigenome of blastocysts produced by IVF. Theriogenology. 2019 Dec 27;144:122-131. doi:10.1016/j.theriogenology.2019.12.020. [Epub ahead of print] PubMed PMID:31951983.

302: Caballero J, Blondin P, Vigneault C, SIRARD MA, Richard FJ. The use of adenosine to inhibit oocyte meiotic resumption in Bos taurus during pre-IVM and its potential to improve oocyte competence. Theriogenology. 2019 Oct 7;142:207-215. doi: 10.1016/j.theriogenology .2019.10.001. [PubMed PMID: 31614287.

301: SIRARD MA. Distribution and dynamics of mitochondrial DNA methylation in oocytes, embryos and granulosa cells. Sci Rep. 2019 Aug 15;9(1):11937. doi: 10.1038/s41598-019-48422-8. PubMed PMID: 31417147; PubMed Central PMCID: PMC6695495.

300: Fortin CS, Leader A, Mahutte N, Hamilton S, Léveillé MC, Villeneuve M, SIRARD MA. Gene expression analysis of follicular cells revealed inflammation as a potential IVF failure cause. J Assist Reprod Genet. 2019 Apr 18. doi: 10.1007/s10815-019-01447-4. PubMed PMID: 31001707.

299: Hue I, Dufort I, Vitorino Carvalho A, Laloe D, Peynot N, Degrelle S, Viebahn C, SIRARD MA. Different pre-implantation phenotypes of bovine blastocysts produced in vitro. Reproduction. 2018 Nov 1.doi:  10.1530/REP-18-0439. PubMed PMID: 30444718.

298: Tscherner A, Brown AC, Stalker L, Kao J, Dufort I, SIRARD MA, LaMarre J. STAT3 signaling stimulates miR-21 expression in bovine cumulus cells during in vitro oocyte maturation. Sci Rep. 2018 Aug 1;8(1):11527. doi:  10.1038/s41598-018-29874-w. PubMed PMID: 30068990.

297: 1: Landry DA, Rossi-Perazza L, Lafontaine S, SIRARD MA. Expression of atresia biomarkers in granulosa cells after ovarian stimulation in heifers. Reproduction. 2018 Jun 15. pii: REP-18-0186. doi: 10.1530/REP-18-0186. [Epub ahead of print] PubMed PMID: 29907662.

296: O’Doherty AM, McGettigan P, Irwin RE, Magee DA, Gagne D, Fournier E, Al-Naib A, SIRARD MA, Walsh CP, Robert C, Fair T. Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies. BMC Genomics. 2018 Jun 5;19(1):438-448

295 Salilew-Wondim D, Saeed-Zidane M, Hoelker M, Gebremedhn S, Poirier M, Pandey HO, Tholen E, Neuhoff C, Held E, Besenfelder U, Havlicek V, Rings F, Fournier E, Gagné D, SIRARD MA, Robert C, Gad A, Schellander K, Tesfaye D. Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation. BMC Genomics. 2018 Jun 1;19(1):424.. PubMed PMID:29859035.

294: Laskowski D, Humblot P, SIRARD MA, Sjunnesson Y, Jhamat N, Båge R, Andersson G. DNA methylation pattern of bovine blastocysts associated to hyperinsulinemia in vitro. Mol Reprod Dev. 2018 May 10. PubMed PMID: 29745447.

293: Landry DA, SIRARD MA. Follicle capacitation: A meta-analysis to investigate the transcriptome dynamics following FSH decline in bovine granulosa cells. Biol  Reprod. 2018 Apr 14. [Epub ahead of print] PubMed PMID: 29668885.

292: Dias FCF, Khan MIR, SIRARD MA, Adams GP, Singh J. Transcriptome analysis of granulosa cells after conventional vs long FSH-induced superstimulation in cattle. BMC Genomics. 2018 Apr 16;19(1):258. PubMed PMID: 29661134.

291: SIRARD MA. 40 years of bovine IVF in the new genomic selection context.  Reproduction. 2018 Apr 10. pii: REP-18-0008. PubMed PMID: 29636405.

290: Laskowski D, Andersson G, Humblot P, SIRARD MA, Sjunnesson Y, Ferreira CR, Pirro V, Båge R. Lipid profile of bovine blastocysts exposed to insulin during in vitro oocyte maturation. Reprod Fertil Dev. 2018 Apr 16. [Epub ahead of print] PubMed PMID: 29655403.

289: Nivet AL, Dufort I, Gilbert I, SIRARD MA. Short-term effect of FSH on gene expression in bovine granulosa cells in vitro. Reprod Fertil Dev. 2018 Mar 13.  doi: 10.1071/RD17469. [Epub ahead of print] PubMed PMID: 29529392.

288: Vachon J, Pagé-Larivière F, SIRARD MA, Rodriguez MJ, Levallois P, Campagna C. Availability, quality and relevance of toxicogenomics data for human health risk assessment: A scoping review of the literature on trihalomethanes. Toxicol Sci.2018 Mar 5. doi:10.1093/toxsci/kfy050. [Epub ahead of print] PubMed PMID: 29514332.

287: SIRARD MA, Grand FX, Labrecque R, Vigneault C, Blondin P. The use of natural cycle’s follicular dynamic to improve oocyte quality in dairy cows and heifers. J Anim Sci. 2018 Mar 3. doi: 10.1093/jas/sky050. [Epub ahead of print] PubMed PMID:  29514310.

286: Ispada J, de Lima CB, SIRARD MA., Fontes PK, Nogueira MFG, Annes K, Milazzotto MP. Genome-wide screening of DNA methylation in bovine blastocysts with different kinetics of development. Epigenetics Chromatin. 2018 Jan 8;11(1):1. PubMed PMID: 29310712.

285: David A. Landry, Rémi Labrecque, François-Xavier Grand, Christian Vigneault, Patrick Blondin and SIRARD MAEffect of heifer age on the granulosa cell transcriptome after ovarian stimulation Reproduction, Fertility and Development 2018: 30 (7)

284:Tremblay R, Dufort I, SIRARD MA. Metabolic Stress Induces Modifications in the Epigenetic Program of Preimplantation Bovine Embryos. Mol Reprod Dev. 2017 Dec 14. [Epub ahead of print] PubMed PMID: 29240275.

283: Luciano AM, SIRARD MA. Successful in vitro maturation of oocytes: a matter of follicular differentiation. Biol Reprod. 2018 Feb 1;98(2):162-169. doi:

282: Lambert S, Blondin P, Vigneault C, Labrecque R, Dufort I, SIRARD MA. Spermatozoa DNA methylation patterns differ due to peripubertal age in bulls. Theriogenology. 2018 Jan 15;106:21-29.

PubMed PMID: 29031946.

281: Lodde V, Luciano AM, Franciosi F, Labrecque R, SIRARD MA. Accumulation of Chromatin Remodelling Enzyme and Histone Transcripts in Bovine Oocytes. Results Probl Cell Differ. 2017;63:223-255. PMID: 28779321.

280: Nivet AL, Vigneault C, Blondin P, SIRARD MA. Influence of luteinizing hormone support on granulosa cells transcriptome in cattle. Anim Sci J. 2018 Jan;89(1):21-30. PMID: 28840634.

Chaire de Recherche du Canada en Génomique de la Reproduction

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