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Pérusse Louis

Membre chercheur régulier

Professeur titulaire
Université Laval
Directeur du Thème 4

Thèmes de recherche

Thème 3 - Alimentation et bien-être

Thème 4 - Personnalisation de la nutrition

Mots clés

génétique

études d'association

Obésité

Coordonnées


  • Université Laval

Professeur titulaire
Faculté de médecine
Département de kinésiologie

Pavillon de l'Éducation physique et des sports - Local 2126
2300 rue de la Terasse
Québec (Québec) G1V 0A6
Canada

418-656-2131 - poste407831

Liens et réseaux sociaux

Expertises


Le Dr Louis Pérusse et son équipe s’intéressent à l’identification de nouveaux gènes de susceptibilité à l’obésité. Leurs efforts portent actuellement sur l’étude des déterminants génétiques des comportements et des apports alimentaires. Ils ont démontré, par des approches de génétique quantitative, qu’il existe des facteurs génétiques communs entre les comportements alimentaires et l’obésité. Au moyen d’études d’association, ils tentent d’identifier des gènes influençant les comportements et les apports alimentaires et de vérifier leur rôle dans la susceptibilité génétique à l’obésité.

Formation


Post-doctorate - Human genetics - University of Michigan

Doctorate - Physical Activity Sciences - Université Laval

Master's Thesis - Physical Activity Sciences - Université Laval

Bachelor's - Biology - Université Laval

En savoir plus


Ma Bibliographie – NCBI

Publications des 5 dernières années

Dietary Mediators of the Genetic Susceptibility to Obesity—Results from the Quebec Family Study The Journal of Nutrition, 2021/11/23. Raphaëlle Jacob, Catherine Bertrand, Clare Llewellyn, Christian Couture, Marie-Ève Labonté, Angelo Tremblay, Claude Bouchard, Vicky Drapeau, Louis Pérusse. DOI 10.1093/jn/nxab356

The fit-active profile to better reflect the benefits of a lifelong vigorous physical activity participation: mini-review of literature and population data. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021/03/05. DOI 10.1139/apnm-2020-1109

Genetic variation in the response to exercise training: impact on physical fitness and performance Principles of Nutrigenetics and Nutrigenomics, 2020.

Integrative Network Analysis of Multi-Omics Data in the Link between Plasma Carotenoid Concentrations and Lipid Profile. Lifestyle genomics, 2019/11/26. DOI 10.1159/000503828

Associations of autozygosity with a broad range of human phenotypes. Nature communications, 2019/10/31. DOI 10.1038/s41467-019-12283-6

The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study. Frontiers in genetics, 2019/10/10. DOI 10.3389/fgene.2019.00994

Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2019/08/31. DOI 10.1016/j.numecd.2019.08.015

Associations Between Dietary Protein Sources, Plasma BCAA and Short-Chain Acylcarnitine Levels in Adults Nutrients, 2019. DOI 10.3390/nu11010173

Familial resemblances in human plasma metabolites are attributable to both genetic and common environmental effects Nutr Res, 2019. DOI 10.1016/j.nutres.2018.10.003

Network Analysis of the Potential Role of DNA Methylation in the Relationship between Plasma Carotenoids and Lipid Profile Nutrients, 2019. DOI 10.3390/nu11061265

Protein intake and the incidence of pre-diabetes and diabetes in 4 population-based studies: the PREVIEW project Am J Clin Nutr, 2019. DOI 10.1093/ajcn/nqy388

The relationship between yogurt consumption, body weight, and metabolic profiles in youth with a familial predisposition to obesity Eur J Clin Nutr, 2019. DOI 10.1038/s41430-018-0166-2

Weighted gene co-expression network analysis to explain the relationship between plasma total carotenoids and lipid profile Genes Nutr, 2019. DOI 10.1186/s12263-019-0639-5

Acute cardiorespiratory responses in participants with heart disease during cycling at different immersion levels Clin Physiol Funct Imaging, 2018. DOI 10.1111/cpf.12389

Acute effects of water immersion on heart rate variability in participants with heart disease Clin Physiol Funct Imaging, 2018. DOI 10.1111/cpf.12405

Familial resemblances in human whole blood transcriptome BMC Genomics, 2018. DOI 10.1186/s12864-018-4698-6

Genetic and Common Environmental Contributions to Familial Resemblances in Plasma Carotenoid Concentrations in Healthy Families Nutrients, 2018. DOI 10.3390/nu10081002

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium Mol Psychiatry, 2018. DOI 10.1038/s41380-018-0079-4

Polygenic risk score for predicting weight loss after bariatric surgery JCI Insight, 2018. DOI 10.1172/jci.insight.122011

The role of eating behavior traits in mediating genetic susceptibility to obesity Am J Clin Nutr, 2018. DOI 10.1093/ajcn/nqy130

Yogurt consumption, body composition, and metabolic health in the Quebec Family Study Eur J Nutr, 2018. DOI 10.1007/s00394-017-1444-9

Acute breathing patterns in healthy and heart disease participants during cycling at different levels of immersion Respir Physiol Neurobiol, 2017. Dionne, A., Leone, M., Andrich, D. E., Pérusse, L., Comtois, A. S.. DOI 10.1016/j.resp.2016.09.011

Genetic regulation of differentially methylated genes in visceral adipose tissue of severely obese men discordant for the metabolic syndrome Transl Res, 2017. Guénard, F., Tchernof, A., Deshaies, Y., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., Pérusse, L., Vohl, M. C.. DOI 10.1016/j.trsl.2017.01.002

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits Nat Commun, 2017. DOI 10.1038/ncomms14977

Genome-wide physical activity interactions in adiposity – A meta-analysis of 200,452 adults PLoS Genet, 2017. Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L. P., Huppertz, C., Willemsen, G., Peyrot, W. J., Wu, Y., Kristiansson, K., Demirkan, A., Fornage, M., Hassinen, M., Bielak, L. F., Cadby, G., Tanaka, T., Mägi, R., van der Most, P. J., Jackson, A. U., Bragg-Gresham, J. L., Vitart, V., Marten, J., Navarro, P., Bellis, C., Pasko, D., Johansson, Å, Snitker, S., Cheng, Y. C., Eriksson, J., Lim, U., Aadahl, M., Adair, L. S., Amin, N., Balkau, B., Auvinen, J., Beilby, J., Bergman, R. N., Bergmann, S., Bertoni, A. G., Blangero, J., Bonnefond, A., Bonnycastle, L. L., Borja, J. B., Brage, S., Busonero, F., Buyske, S., Campbell, H., Chines, P. S., Collins, F. S., Corre, T., Smith, G. D., Delgado, G. E., Dueker, N., Dörr, M., Ebeling, T., Eiriksdottir, G., Esko, T., Faul, J. D., Fu, M., Færch, K., Gieger, C., Gläser, S., Gong, J., Gordon-Larsen, P., Grallert, H., Grammer, T. B., Grarup, N., van Grootheest, G., Harald, K., Hastie, N. D., Havulinna, A. S., Hernandez, D., Hindorff, L., Hocking, L. J., Holmens, O. L., Holzapfel, C., Hottenga, J. J., Huang, J., Huang, T., Hui, J., Huth, C., Hutri-Kähönen, N., James, A. L., Jansson, J. O., Jhun, M. A., Juonala, M., Kinnunen, L., Koistinen, H. A., Kolcic, I., Komulainen, P., Kuusisto, J., Kvaløy, K., Kähönen, M., Lakka, T. A., Launer, L. J., Lehne, B., Lindgren, C. M., Lorentzon, M., Luben, R., Marre, M., Milaneschi, Y., Monda, K. L., Montgomery, G. W., De Moor, M. H. M., Mulas, A., Müller-Nurasyid, M., Musk, A. W., Männikkö, R., Männistö, S., Narisu, N., Nauck, M., Nettleton, J. A., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Paternoster, L., Perez, J., Perola, M., Peters, A., Peters, U., Peyser, P. A., Prokopenko, I., Puolijoki, H., Raitakari, O. T., Rankinen, T., Rasmussen-Torvik, L. J., Rawal, R., Ridker, P. M., Rose, L. M., Rudan, I., Sarti, C., Sarzynski, M. A., Savonen, K., Scott, W. R., Sanna, S., Shuldiner, A. R., Sidney, S., Silbernagel, G., Smith, B. H., Smith, J. A., Snieder, H., Stančáková, A., Sternfeld, B., Swift, A. J., Tammelin, T., Tan, S. T., Thorand, B., Thuillier, D., Vandenput, L., Vestergaard, H., van Vliet-Ostaptchouk, J. V., Vohl, M. C., Völker, U., Waeber, G., Walker, M., Wild, S., Wong, A., Wright, A. F., Zillikens, M. C., Zubair, N., Haiman, C. A., Lemarchand, L., Gyllensten, U., Ohlsson, C., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pérusse, L., Wilson, J. F., Hayward, C., Polasek, O., Cucca, F., Hveem, K., Hartman, C. A., Tönjes, A., Bandinelli, S., Palmer, L. J., Kardia, S. L. R., Rauramaa, R., Sørensen, T. I. A., Tuomilehto, J., Salomaa, V., Penninx, B. W. J.H, de Geus, E. J. C., Boomsma, D. I., Lehtimäki, T., Mangino, M., Laakso, M., Bouchard, C., Martin, N. G., Kuh, D., Liu, Y., Linneberg, A., März, W., Strauch, K., Kivimäki, M., Harris, T. B., Gudnason, V., Völzke, H., Qi, L., Järvelin, M. R., Chambers, J. C., Kooner, J. S., Froguel, P., Kooperberg, C., Vollenweider, P., Hallmans, G., Hansen, T., Pedersen, O., Metspalu, A., Wareham, N. J., Langenberg, C., Weir, D. R., Porteous, D. J., Boerwinkle, E., Chasman, D. I., Abecasis, G. R., Barroso, I., McCarthy, M. I., Frayling, T. M., O’Connell, J. R., van Duijn, C. M., Boehnke, M., Heid, I. M., Mohlke, K. L., Strachan, D. P., Fox, C. S., Liu, C. T., Hirschhorn, J. N., Klein, R. J., Johnson, A. D., Borecki, I. B., Franks, P. W., North, K. E., Cupples, L. A., Loos, R. J. F., Kilpeläinen, T. O., CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium. DOI 10.1371/journal.pgen.1006528

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity J Nutrigenet Nutrigenomics, 2017. Ramos-Lopez, O., Milagro, F. I., Allayee, H., Chmurzynska, A., Choi, M. S., Curi, R., De Caterina, R., Ferguson, L. R., Goni, L., Kang, J. X., Kohlmeier, M., Marti, A., Moreno, L. A., Pérusse, L., Prasad, C., Qi, L., Reifen, R., Riezu-Boj, J. I., San-Cristobal, R., Santos, J. L., Martínez, J. A.. DOI 10.1159/000477729

Obesity, genes, and sleep habits Am J Clin Nutr, 2017. Tremblay, A., Pérusse, L.. DOI 10.3945/ajcn.117.154252

The economic consequences of obesity and overweight among adults in Quebec Can J Public Health, 2017. Blouin, C., Hamel, D., Vandal, N., Barry, A. D., Lo, E., Lacroix, G., Laguë, J., Langlois, M. F., Martel, S., Michaud, P. C., Pérusse, L..

[Susceptibilité à l’obésité : rôle des déterminants génétiques des comportements alimentaires] Can J Diet Pract Res, 2017. Jacob, R., Tremblay, A., Drapeau, V., Provencher, V., Pérusse, L.. DOI 10.3148/cjdpr-2017-019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature communications, 2016/11/23. DOI 10.1038/ncomms13357

A GWAS follow-up of obesity-related SNPs in SYPL2 reveals sex-specific association with hip circumference. Obesity science & practice, 2016/10/21. DOI 10.1002/osp4.74

Advances in Exercise, Fitness, and Performance Genomics in 2015. Medicine and science in sports and exercise, 2016/10/01. DOI 10.1249/mss.0000000000000982

Familial resemblances in blood leukocyte DNA methylation levels. Epigenetics, 2016/09/09. DOI 10.1080/15592294.2016.1232234

Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status. Nutrients, 2016/05/27. DOI 10.3390/nu8060324

Yogurt consumption: influence of body mass index and dietary restraint – Cross sectional analysis of the INFOGENE study J Food Nutr Diete, 2016/05/09.

Impact of NMT1 Gene Polymorphisms on Features of the Metabolic Syndrome among Severely Obese Patients Obesity Research – Open Journal, 2016/03/28. DOI 10.17140/oroj-2-116

A CpG-SNP Located within the ARPC3 Gene Promoter Is Associated with Hypertriglyceridemia in Severely Obese Patients Ann Nutr Metab, 2016. de Toro-Martín, J., Guénard, F., Tchernof, A., Deshaies, Y., Pérusse, L., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., Vohl, M. C.. DOI 10.1159/000445358

Association between yogurt consumption, dietary patterns, and cardio-metabolic risk factors Eur J Nutr, 2016. Cormier, H., Thifault, É, Garneau, V., Tremblay, A., Drapeau, V., Pérusse, L., Vohl, M. C.. DOI 10.1007/s00394-015-0878-1

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat Int J Obes (Lond), 2016. Sung, Y. J., Pérusse, L., Sarzynski, M. A., Fornage, M., Sidney, S., Sternfeld, B., Rice, T., Terry, J. G., Jacobs, D. R., Katzmarzyk, P., Curran, J. E., Jeffrey Carr, J., Blangero, J., Ghosh, S., Després, J. P., Rankinen, T., Rao, D. C., Bouchard, C.. DOI 10.1038/ijo.2015.217

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels Nat Commun, 2016. Kilpeläinen, T. O., Carli, J. F., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, ÅK, Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L. P., Eriksson, J., Henneman, P., Lahti, J., Tanaka, T., Luan, J., Greco M, F. D., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y. D., de Craen, A. J., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J. O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K. H., LeDuc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., van Heemst, D., Uh, H. W., Vohl, M. C., Walker, M., Wichmann, H. E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, T. I., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., van Dijk, K. W., van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L., Loos, R. J.. DOI 10.1038/ncomms10494

Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects Diabetol Metab Syndr, 2016. de Toro-Martín, J., Guénard, F., Tchernof, A., Deshaies, Y., Pérusse, L., Hould, F. S., Lebel, S., Marceau, P., Vohl, M. C.. DOI 10.1186/s13098-016-0171-3

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk Nat Commun, 2016. Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, ÅK, Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S., Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., de Groot, L. C., De Jager, P. L., Dhonukshe-Rutten, R. A., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B. G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Mateo Leach, I., Lee, C. G., Lee, J. Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikäinen, L. P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Narančić, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M., Taittonen, L., Tanaka, T., Tikkanen, E., van der Velde, N., van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., Mcknight, B., Menni, C., O’Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., Mckenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., van der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M. C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpeläinen, T. O., Loos, R. J.. DOI 10.1038/ncomms10495

No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes PLoS One, 2016. Rankinen, T., Fuku, N., Wolfarth, B., Wang, G., Sarzynski, M. A., Alexeev, D. G., Ahmetov, I. I., Boulay, M. R., Cieszczyk, P., Eynon, N., Filipenko, M. L., Garton, F. C., Generozov, E. V., Govorun, V. M., Houweling, P. J., Kawahara, T., Kostryukova, E. S., Kulemin, N. A., Larin, A. K., Maciejewska-Karłowska, A., Miyachi, M., Muniesa, C. A., Murakami, H., Ospanova, E. A., Padmanabhan, S., Pavlenko, A. V., Pyankova, O. N., Santiago, C., Sawczuk, M., Scott, R. A., Uyba, V. V., Yvert, T., Perusse, L., Ghosh, S., Rauramaa, R., North, K. N., Lucia, A., Pitsiladis, Y., Bouchard, C.. DOI 10.1371/journal.pone.0147330

The rare allele of DGKZ SNP rs10838599 is associated with variability in HDL-cholesterol levels among severely obese patients Integrative Obesity and Diabetes, 2016. DOI 10.15761/iod.1000148

 

 

2021/10 – 2024/9 – Chercheur principal

Identifying nutrition and lifestyle mediators of genetic susceptibility to obesity: towards a precision lifestyle medicine approach to obesity prevention
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Montant total – 252,450$

 

2020/4 – 2024/3 – C0-chercheur

Predicting weight loss and metabolic improvements after bariatric surgery through a novel genetic and epigenetic score
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Montant total – 459,000$
Chercheure principale: Marie-Claude Vohl

 

President, International Society of Nutrigenetics and Nutrigenomics (ISNN).

Editorial Board member of Lifestyle Genomics

Member Réseau de médecine génétique appliquée du Québec, FRQS.

Member American Society of Human Genetics (ASHG).

Member American Society of Nutrition (ASN).

Among the 20 most prolific researchers worldwide in the field of obesity, according to a Science Watch survey.

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Pérusse Louis

Membre chercheur régulier, Membre chercheur régulier

Professeur titulaire
Université Laval
Directeur du Thème 4

Thèmes de recherche

Thème 3 - Alimentation et bien-être

Thème 4 - Personnalisation de la nutrition

Mots clés

Obésité

génétique

études d’association

Coordonnées


  • Université Laval

Professeur titulaire
Faculté de médecine
Département de kinésiologie

Pavillon de l'Éducation physique et des sports - Local 2126
2300 rue de la Terasse
Québec (Québec) G1V 0A6
Canada

418-656-2131 - poste407831

Liens et réseaux sociaux

Expertises


Le Dr Louis Pérusse et son équipe s’intéressent à l’identification de nouveaux gènes de susceptibilité à l’obésité. Leurs efforts portent actuellement sur l’étude des déterminants génétiques des comportements et des apports alimentaires. Ils ont démontré, par des approches de génétique quantitative, qu’il existe des facteurs génétiques communs entre les comportements alimentaires et l’obésité. Au moyen d’études d’association, ils tentent d’identifier des gènes influençant les comportements et les apports alimentaires et de vérifier leur rôle dans la susceptibilité génétique à l’obésité.

Formation


Post-doctorate - Human genetics - University of Michigan

Doctorate - Physical Activity Sciences - Université Laval

Master's Thesis - Physical Activity Sciences - Université Laval

Bachelor's - Biology - Université Laval

En savoir plus


Ma Bibliographie – NCBI

Publications des 5 dernières années

Dietary Mediators of the Genetic Susceptibility to Obesity—Results from the Quebec Family Study The Journal of Nutrition, 2021/11/23. Raphaëlle Jacob, Catherine Bertrand, Clare Llewellyn, Christian Couture, Marie-Ève Labonté, Angelo Tremblay, Claude Bouchard, Vicky Drapeau, Louis Pérusse. DOI 10.1093/jn/nxab356

The fit-active profile to better reflect the benefits of a lifelong vigorous physical activity participation: mini-review of literature and population data. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021/03/05. DOI 10.1139/apnm-2020-1109

Genetic variation in the response to exercise training: impact on physical fitness and performance Principles of Nutrigenetics and Nutrigenomics, 2020.

Integrative Network Analysis of Multi-Omics Data in the Link between Plasma Carotenoid Concentrations and Lipid Profile. Lifestyle genomics, 2019/11/26. DOI 10.1159/000503828

Associations of autozygosity with a broad range of human phenotypes. Nature communications, 2019/10/31. DOI 10.1038/s41467-019-12283-6

The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study. Frontiers in genetics, 2019/10/10. DOI 10.3389/fgene.2019.00994

Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2019/08/31. DOI 10.1016/j.numecd.2019.08.015

Associations Between Dietary Protein Sources, Plasma BCAA and Short-Chain Acylcarnitine Levels in Adults Nutrients, 2019. DOI 10.3390/nu11010173

Familial resemblances in human plasma metabolites are attributable to both genetic and common environmental effects Nutr Res, 2019. DOI 10.1016/j.nutres.2018.10.003

Network Analysis of the Potential Role of DNA Methylation in the Relationship between Plasma Carotenoids and Lipid Profile Nutrients, 2019. DOI 10.3390/nu11061265

Protein intake and the incidence of pre-diabetes and diabetes in 4 population-based studies: the PREVIEW project Am J Clin Nutr, 2019. DOI 10.1093/ajcn/nqy388

The relationship between yogurt consumption, body weight, and metabolic profiles in youth with a familial predisposition to obesity Eur J Clin Nutr, 2019. DOI 10.1038/s41430-018-0166-2

Weighted gene co-expression network analysis to explain the relationship between plasma total carotenoids and lipid profile Genes Nutr, 2019. DOI 10.1186/s12263-019-0639-5

Acute cardiorespiratory responses in participants with heart disease during cycling at different immersion levels Clin Physiol Funct Imaging, 2018. DOI 10.1111/cpf.12389

Acute effects of water immersion on heart rate variability in participants with heart disease Clin Physiol Funct Imaging, 2018. DOI 10.1111/cpf.12405

Familial resemblances in human whole blood transcriptome BMC Genomics, 2018. DOI 10.1186/s12864-018-4698-6

Genetic and Common Environmental Contributions to Familial Resemblances in Plasma Carotenoid Concentrations in Healthy Families Nutrients, 2018. DOI 10.3390/nu10081002

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium Mol Psychiatry, 2018. DOI 10.1038/s41380-018-0079-4

Polygenic risk score for predicting weight loss after bariatric surgery JCI Insight, 2018. DOI 10.1172/jci.insight.122011

The role of eating behavior traits in mediating genetic susceptibility to obesity Am J Clin Nutr, 2018. DOI 10.1093/ajcn/nqy130

Yogurt consumption, body composition, and metabolic health in the Quebec Family Study Eur J Nutr, 2018. DOI 10.1007/s00394-017-1444-9

Acute breathing patterns in healthy and heart disease participants during cycling at different levels of immersion Respir Physiol Neurobiol, 2017. Dionne, A., Leone, M., Andrich, D. E., Pérusse, L., Comtois, A. S.. DOI 10.1016/j.resp.2016.09.011

Genetic regulation of differentially methylated genes in visceral adipose tissue of severely obese men discordant for the metabolic syndrome Transl Res, 2017. Guénard, F., Tchernof, A., Deshaies, Y., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., Pérusse, L., Vohl, M. C.. DOI 10.1016/j.trsl.2017.01.002

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits Nat Commun, 2017. DOI 10.1038/ncomms14977

Genome-wide physical activity interactions in adiposity – A meta-analysis of 200,452 adults PLoS Genet, 2017. Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L. P., Huppertz, C., Willemsen, G., Peyrot, W. J., Wu, Y., Kristiansson, K., Demirkan, A., Fornage, M., Hassinen, M., Bielak, L. F., Cadby, G., Tanaka, T., Mägi, R., van der Most, P. J., Jackson, A. U., Bragg-Gresham, J. L., Vitart, V., Marten, J., Navarro, P., Bellis, C., Pasko, D., Johansson, Å, Snitker, S., Cheng, Y. C., Eriksson, J., Lim, U., Aadahl, M., Adair, L. S., Amin, N., Balkau, B., Auvinen, J., Beilby, J., Bergman, R. N., Bergmann, S., Bertoni, A. G., Blangero, J., Bonnefond, A., Bonnycastle, L. L., Borja, J. B., Brage, S., Busonero, F., Buyske, S., Campbell, H., Chines, P. S., Collins, F. S., Corre, T., Smith, G. D., Delgado, G. E., Dueker, N., Dörr, M., Ebeling, T., Eiriksdottir, G., Esko, T., Faul, J. D., Fu, M., Færch, K., Gieger, C., Gläser, S., Gong, J., Gordon-Larsen, P., Grallert, H., Grammer, T. B., Grarup, N., van Grootheest, G., Harald, K., Hastie, N. D., Havulinna, A. S., Hernandez, D., Hindorff, L., Hocking, L. J., Holmens, O. L., Holzapfel, C., Hottenga, J. J., Huang, J., Huang, T., Hui, J., Huth, C., Hutri-Kähönen, N., James, A. L., Jansson, J. O., Jhun, M. A., Juonala, M., Kinnunen, L., Koistinen, H. A., Kolcic, I., Komulainen, P., Kuusisto, J., Kvaløy, K., Kähönen, M., Lakka, T. A., Launer, L. J., Lehne, B., Lindgren, C. M., Lorentzon, M., Luben, R., Marre, M., Milaneschi, Y., Monda, K. L., Montgomery, G. W., De Moor, M. H. M., Mulas, A., Müller-Nurasyid, M., Musk, A. W., Männikkö, R., Männistö, S., Narisu, N., Nauck, M., Nettleton, J. A., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Paternoster, L., Perez, J., Perola, M., Peters, A., Peters, U., Peyser, P. A., Prokopenko, I., Puolijoki, H., Raitakari, O. T., Rankinen, T., Rasmussen-Torvik, L. J., Rawal, R., Ridker, P. M., Rose, L. M., Rudan, I., Sarti, C., Sarzynski, M. A., Savonen, K., Scott, W. R., Sanna, S., Shuldiner, A. R., Sidney, S., Silbernagel, G., Smith, B. H., Smith, J. A., Snieder, H., Stančáková, A., Sternfeld, B., Swift, A. J., Tammelin, T., Tan, S. T., Thorand, B., Thuillier, D., Vandenput, L., Vestergaard, H., van Vliet-Ostaptchouk, J. V., Vohl, M. C., Völker, U., Waeber, G., Walker, M., Wild, S., Wong, A., Wright, A. F., Zillikens, M. C., Zubair, N., Haiman, C. A., Lemarchand, L., Gyllensten, U., Ohlsson, C., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pérusse, L., Wilson, J. F., Hayward, C., Polasek, O., Cucca, F., Hveem, K., Hartman, C. A., Tönjes, A., Bandinelli, S., Palmer, L. J., Kardia, S. L. R., Rauramaa, R., Sørensen, T. I. A., Tuomilehto, J., Salomaa, V., Penninx, B. W. J.H, de Geus, E. J. C., Boomsma, D. I., Lehtimäki, T., Mangino, M., Laakso, M., Bouchard, C., Martin, N. G., Kuh, D., Liu, Y., Linneberg, A., März, W., Strauch, K., Kivimäki, M., Harris, T. B., Gudnason, V., Völzke, H., Qi, L., Järvelin, M. R., Chambers, J. C., Kooner, J. S., Froguel, P., Kooperberg, C., Vollenweider, P., Hallmans, G., Hansen, T., Pedersen, O., Metspalu, A., Wareham, N. J., Langenberg, C., Weir, D. R., Porteous, D. J., Boerwinkle, E., Chasman, D. I., Abecasis, G. R., Barroso, I., McCarthy, M. I., Frayling, T. M., O’Connell, J. R., van Duijn, C. M., Boehnke, M., Heid, I. M., Mohlke, K. L., Strachan, D. P., Fox, C. S., Liu, C. T., Hirschhorn, J. N., Klein, R. J., Johnson, A. D., Borecki, I. B., Franks, P. W., North, K. E., Cupples, L. A., Loos, R. J. F., Kilpeläinen, T. O., CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium. DOI 10.1371/journal.pgen.1006528

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity J Nutrigenet Nutrigenomics, 2017. Ramos-Lopez, O., Milagro, F. I., Allayee, H., Chmurzynska, A., Choi, M. S., Curi, R., De Caterina, R., Ferguson, L. R., Goni, L., Kang, J. X., Kohlmeier, M., Marti, A., Moreno, L. A., Pérusse, L., Prasad, C., Qi, L., Reifen, R., Riezu-Boj, J. I., San-Cristobal, R., Santos, J. L., Martínez, J. A.. DOI 10.1159/000477729

Obesity, genes, and sleep habits Am J Clin Nutr, 2017. Tremblay, A., Pérusse, L.. DOI 10.3945/ajcn.117.154252

The economic consequences of obesity and overweight among adults in Quebec Can J Public Health, 2017. Blouin, C., Hamel, D., Vandal, N., Barry, A. D., Lo, E., Lacroix, G., Laguë, J., Langlois, M. F., Martel, S., Michaud, P. C., Pérusse, L..

[Susceptibilité à l’obésité : rôle des déterminants génétiques des comportements alimentaires] Can J Diet Pract Res, 2017. Jacob, R., Tremblay, A., Drapeau, V., Provencher, V., Pérusse, L.. DOI 10.3148/cjdpr-2017-019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature communications, 2016/11/23. DOI 10.1038/ncomms13357

A GWAS follow-up of obesity-related SNPs in SYPL2 reveals sex-specific association with hip circumference. Obesity science & practice, 2016/10/21. DOI 10.1002/osp4.74

Advances in Exercise, Fitness, and Performance Genomics in 2015. Medicine and science in sports and exercise, 2016/10/01. DOI 10.1249/mss.0000000000000982

Familial resemblances in blood leukocyte DNA methylation levels. Epigenetics, 2016/09/09. DOI 10.1080/15592294.2016.1232234

Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status. Nutrients, 2016/05/27. DOI 10.3390/nu8060324

Yogurt consumption: influence of body mass index and dietary restraint – Cross sectional analysis of the INFOGENE study J Food Nutr Diete, 2016/05/09.

Impact of NMT1 Gene Polymorphisms on Features of the Metabolic Syndrome among Severely Obese Patients Obesity Research – Open Journal, 2016/03/28. DOI 10.17140/oroj-2-116

A CpG-SNP Located within the ARPC3 Gene Promoter Is Associated with Hypertriglyceridemia in Severely Obese Patients Ann Nutr Metab, 2016. de Toro-Martín, J., Guénard, F., Tchernof, A., Deshaies, Y., Pérusse, L., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., Vohl, M. C.. DOI 10.1159/000445358

Association between yogurt consumption, dietary patterns, and cardio-metabolic risk factors Eur J Nutr, 2016. Cormier, H., Thifault, É, Garneau, V., Tremblay, A., Drapeau, V., Pérusse, L., Vohl, M. C.. DOI 10.1007/s00394-015-0878-1

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat Int J Obes (Lond), 2016. Sung, Y. J., Pérusse, L., Sarzynski, M. A., Fornage, M., Sidney, S., Sternfeld, B., Rice, T., Terry, J. G., Jacobs, D. R., Katzmarzyk, P., Curran, J. E., Jeffrey Carr, J., Blangero, J., Ghosh, S., Després, J. P., Rankinen, T., Rao, D. C., Bouchard, C.. DOI 10.1038/ijo.2015.217

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels Nat Commun, 2016. Kilpeläinen, T. O., Carli, J. F., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, ÅK, Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L. P., Eriksson, J., Henneman, P., Lahti, J., Tanaka, T., Luan, J., Greco M, F. D., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y. D., de Craen, A. J., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J. O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K. H., LeDuc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., van Heemst, D., Uh, H. W., Vohl, M. C., Walker, M., Wichmann, H. E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, T. I., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., van Dijk, K. W., van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L., Loos, R. J.. DOI 10.1038/ncomms10494

Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects Diabetol Metab Syndr, 2016. de Toro-Martín, J., Guénard, F., Tchernof, A., Deshaies, Y., Pérusse, L., Hould, F. S., Lebel, S., Marceau, P., Vohl, M. C.. DOI 10.1186/s13098-016-0171-3

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk Nat Commun, 2016. Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, ÅK, Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S., Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., de Groot, L. C., De Jager, P. L., Dhonukshe-Rutten, R. A., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B. G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Mateo Leach, I., Lee, C. G., Lee, J. Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikäinen, L. P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Narančić, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M., Taittonen, L., Tanaka, T., Tikkanen, E., van der Velde, N., van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., Mcknight, B., Menni, C., O’Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., Mckenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., van der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M. C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpeläinen, T. O., Loos, R. J.. DOI 10.1038/ncomms10495

No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes PLoS One, 2016. Rankinen, T., Fuku, N., Wolfarth, B., Wang, G., Sarzynski, M. A., Alexeev, D. G., Ahmetov, I. I., Boulay, M. R., Cieszczyk, P., Eynon, N., Filipenko, M. L., Garton, F. C., Generozov, E. V., Govorun, V. M., Houweling, P. J., Kawahara, T., Kostryukova, E. S., Kulemin, N. A., Larin, A. K., Maciejewska-Karłowska, A., Miyachi, M., Muniesa, C. A., Murakami, H., Ospanova, E. A., Padmanabhan, S., Pavlenko, A. V., Pyankova, O. N., Santiago, C., Sawczuk, M., Scott, R. A., Uyba, V. V., Yvert, T., Perusse, L., Ghosh, S., Rauramaa, R., North, K. N., Lucia, A., Pitsiladis, Y., Bouchard, C.. DOI 10.1371/journal.pone.0147330

The rare allele of DGKZ SNP rs10838599 is associated with variability in HDL-cholesterol levels among severely obese patients Integrative Obesity and Diabetes, 2016. DOI 10.15761/iod.1000148

 

 

2021/10 – 2024/9 – Chercheur principal

Identifying nutrition and lifestyle mediators of genetic susceptibility to obesity: towards a precision lifestyle medicine approach to obesity prevention
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Montant total – 252,450$

 

2020/4 – 2024/3 – C0-chercheur

Predicting weight loss and metabolic improvements after bariatric surgery through a novel genetic and epigenetic score
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Montant total – 459,000$
Chercheure principale: Marie-Claude Vohl

 

President, International Society of Nutrigenetics and Nutrigenomics (ISNN).

Editorial Board member of Lifestyle Genomics

Member Réseau de médecine génétique appliquée du Québec, FRQS.

Member American Society of Human Genetics (ASHG).

Member American Society of Nutrition (ASN).

Among the 20 most prolific researchers worldwide in the field of obesity, according to a Science Watch survey.